Brain-Related Proteins in Blood Reveal the Effects of Blast Exposure

Blast overpressure is a displacement of air above normal levels generated by heavy caliber weapons or from explosives. Service Members are routinely exposed to blast overpressure during combat and training exercises, and many suffer difficulty thinking or ringing of the ears (tinnitus). Blast-related symptoms are similar to brain injury, but are much more subtle and difficult to measure. Measurement of biomarkers - characteristics of the body - is increasingly common for understanding brain injury. The same biomarkers studied for a diagnosed brain injury, were found within hours of blast overpressure exposure, even when symptoms were not apparent. These blood-derived biomarkers have the potential to serve indicators of blast overpressure exposure and monitoring Soldier health.


These studies were originally featured in


PLoS One

Brain-related proteins as serum biomarkers of acute, subconcussive blast overpressure exposure: A cohort study of military personnel

Angela M Boutté, Bharani Thangavelu, Christina R LaValle, Jeffrey Nemes, Janice Gilsdorf, Deborah A Shear, Gary H Kamimori

( https://doi.org/10.1371/journal.pone.0221036 )


&


Frontiers Neurology

Overpressure Exposure From .50-Caliber Rifle Training Is Associated With Increased Amyloid Beta Peptides in Serum

Bharani Thangavelu, Christina R LaValle, Michael J Egnoto, Jeffrey Nemes, Angela M Boutté, Gary H Kamimori

( https://doi.org/10.3389/fneur.2020.00620 )


To learn how our expertise in brain biomarkers can augment your research needs, visit Aries Biotech at https://www.ariesbiotechnologies.org.

3 views0 comments

Recent Posts

See All

Honored to serve as a guest speaker for the event “Do You Want To Be A Neuroscientist?” hosted by the Careers Centre and the School of Psychology and Neuroscience. A link to the event may be found he

We look forward to continuing to provide you with consultation services. More great things to come in 2022! To learn how we can assist with your needs within science and medicine, visit Aries Biotech